PAX6 Protein (His tag)

Catalog No. ABIN2728323

Product Details

Target: PAX6 (Paired Box 6 (PAX6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PAX6 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PAX6 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: Pax6 (PAX6 Products)

Synonyms: pax6 Protein, an2 Protein, mgda Protein, wagr Protein, pax-6 Protein, pax6a Protein, xpax6 Protein, XLPAX6 Protein, MGC52531 Protein, PAX-6 Protein, AN Protein, AN2 Protein, D11S812E Protein, MGDA Protein, WAGR Protein, Pax-6 Protein, pax6b Protein, 1500038E17Rik Protein, AEY11 Protein, Dey Protein, Gsfaey11 Protein, Sey Protein, PAXZF-A Protein, Pax6.1 Protein, cb280 Protein, fc20e07 Protein, pax-a Protein, pax[zf-a] Protein, paxzfa Protein, wu:fc20e07 Protein, zfpax-6a Protein, zfpax-6b Protein, paired box 6 Protein, paired box 6 L homeolog Protein, paired box 6 S homeolog Protein, paired box 6a Protein, PAX6 Protein, pax6 Protein, Pax6 Protein, pax6.L Protein, pax6.S Protein, pax6a Protein

Background: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Molecular Weight: 48 kDa

NCBI Accession: NP_001595

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis