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PCDHA4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

PCDHA4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728388
  • Target See all PCDHA4 Proteins
    PCDHA4 (Protocadherin alpha 4 (PCDHA4))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 4
    Human
    Source
    • 6
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PCDHA4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PCDHA4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PCDHA4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PCDHA4 (Protocadherin alpha 4 (PCDHA4))
    Alternative Name
    Pcdha4 (PCDHA4 Products)
    Synonyms
    CNR1 Protein, CNRN1 Protein, CRNR1 Protein, PCDH-ALPHA4 Protein, Cnr1 Protein, Crnr1 Protein, R75250 Protein, PCDHA4 Protein, CNRv4 Protein, Pcdha4 Protein, protocadherin alpha 4 Protein, protocadherin alpha-4 Protein, PCDHA4 Protein, Pcdha4 Protein, LOC100713594 Protein, LOC100629843 Protein
    Background
    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Molecular Weight
    82.9 kDa
    NCBI Accession
    NP_113688
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