PDCD10 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728460

Product Details

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PDCD10 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PDCD10 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Alternative Name: Pdcd10 (PDCD10 Products)

Synonyms: CCM3 Protein, TFAR15 Protein, 2410003B13Rik Protein, Ccm3 Protein, Tfa15 Protein, Tfar15 Protein, zgc:85629 Protein, ccm3a Protein, pdcd10 Protein, zgc:65826 Protein, programmed cell death 10 Protein, programmed cell death 10 S homeolog Protein, programmed cell death 10b Protein, programmed cell death 10a Protein, PDCD10 Protein, Pdcd10 Protein, pdcd10.S Protein, pdcd10b Protein, pdcd10a Protein

Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 24.5 kDa

NCBI Accession: NP_009148