PDE11A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Target See all PDE11A Proteins
- PDE11A (phosphodiesterase 11A (PDE11A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 4
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDE11A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDE11A (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDE11A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDE11A (phosphodiesterase 11A (PDE11A))
- Alternative Name
- Pde11a (PDE11A Products)
- Synonyms
- PPNAD2 Protein, 6330414F14Rik Protein, A630086N24Rik Protein, Gm350 Protein, PDE11A1 Protein, si:ch211-222f23.5 Protein, PDE11A Protein, ppnad2 Protein, Pde11a Protein, phosphodiesterase 11A Protein, phosphodiesterase 11a Protein, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Protein, PDE11A Protein, Pde11a Protein, pde11a Protein, LOC100470038 Protein
- Background
- The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 104.6 kDa
- NCBI Accession
- NP_058649
- Pathways
- cAMP Metabolic Process
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