PRPH2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728685

Product Details

Target: PRPH2 (Peripherin 2 (Retinal Degeneration, Slow) (PRPH2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PRPH2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Peripherin-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRPH2 (Peripherin 2 (Retinal Degeneration, Slow) (PRPH2))

Alternative Name: Peripherin-2 (PRPH2 Products)

Synonyms: AOFMD Protein, AVMD Protein, Nmf193 Protein, PRPH Protein, RP7 Protein, Rd-2 Protein, Rd2 Protein, Rds Protein, Tspan22 Protein, rds Protein, RSRDS Protein, CACD2 Protein, DS Protein, RDS Protein, TSPAN22 Protein, rd2 Protein, CRDS1 Protein, prph-2 Protein, prph2b Protein, rds38 Protein, peripherin 2 Protein, peripherin 2 (retinal degeneration, slow) S homeolog Protein, Prph2 Protein, PRPH2 Protein, prph2.S Protein

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic.

Molecular Weight: 39.1 kDa

NCBI Accession: NP_000313