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PPHLN1 Protein (Transcript Variant 8) (Myc-DYKDDDDK Tag)

PPHLN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728687
  • Target See all PPHLN1 Proteins
    PPHLN1 (Periphilin 1 (PPHLN1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 8
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PPHLN1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Periphilin 1 (PPHLN1), transcript variant 8 (transcript variant 8) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPHLN1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PPHLN1 (Periphilin 1 (PPHLN1))
    Abstract
    PPHLN1 Products
    Synonyms
    MGC75908 Protein, MGC81987 Protein, wu:fb83c09 Protein, zgc:158246 Protein, si:ch211-155a11.2 Protein, HSPC232 Protein, 1110063K05Rik Protein, 1600022A19Rik Protein, CR Protein, HSPC206 Protein, periphilin 1 Protein, periphilin 1 S homeolog Protein, PPHLN1 Protein, pphln1 Protein, pphln1.S Protein, Pphln1 Protein
    Background
    The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Molecular Weight
    33.7 kDa
    NCBI Accession
    NP_001137261
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