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PFKFB1 Protein (His tag)

PFKFB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728746
  • Target See all PFKFB1 Proteins
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PFKFB1 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PFKFB1 (full length, N-term HIS tag) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PFKFB1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Alternative Name
    Pfkfb1 (PFKFB1 Products)
    Synonyms
    zgc:55328 Protein, wu:fi11h10 Protein, PFKFB1 Protein, F6PK Protein, HL2K Protein, PFRX Protein, Pfkfb01 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Protein, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Protein, pfkfb1 Protein, PFKFB1 Protein, pfkfb1.S Protein, LOC100475853 Protein, Pfkfb1 Protein
    Background
    This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    54.5 kDa
    NCBI Accession
    NP_002616
    Pathways
    Regulation of Carbohydrate Metabolic Process
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