PGPEP1 Protein (Myc-DYKDDDDK Tag)
-
- Target See all PGPEP1 Proteins
- PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PGPEP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human PGPEP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PGPEP1 Protein
-
Pyroglutamyl-Peptidase I (PGPEP1) (AA 1-209) protein (His tag)
PGPEP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Pyroglutamyl-Peptidase I (PGPEP1) (AA 1-209) protein (GST tag)PGPEP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Pyroglutamyl-Peptidase I (PGPEP1) (AA 1-209) protein (Strep Tag)Crystallography grade PGPEP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Pyroglutamyl-Peptidase I (PGPEP1) (AA 1-209) protein (Strep Tag)Crystallography grade PGPEP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
- Alternative Name
- Pgpep1 (PGPEP1 Products)
- Synonyms
- PGP Protein, PGP-I Protein, PGPI Protein, Pcp Protein, 2810003H13Rik Protein, Gm19458 Protein, PAP-I Protein, PAPI Protein, pyroglutamyl-peptidase I Protein, Pyroglutamyl-peptidase I Protein, Fnod_0998 Protein, Tlet_1256 Protein, Franean1_3440 Protein, Sked_37410 Protein, Arch_1014 Protein, Olsu_1567 Protein, Bcell_2984 Protein, Deima_2337 Protein, Spico_0458 Protein, Poras_1572 Protein, PGPEP1 Protein, Pgpep1 Protein
- Background
- The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity.
- Molecular Weight
- 23 kDa
- NCBI Accession
- NP_060182
-
