PHKA2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728840

Product Details

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PHKA2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PHKA2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Alternative Name: Phka2 (PHKA2 Products)

Synonyms: GSD9A Protein, PHK Protein, PYK Protein, PYKL Protein, XLG Protein, XLG2 Protein, PHKA2 Protein, 6330505C01Rik Protein, D330034O08 Protein, Phk Protein, phosphorylase kinase regulatory subunit alpha 2 Protein, phosphorylase kinase alpha 2 Protein, PHKA2 Protein, Phka2 Protein

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010].

Molecular Weight: 138.2 kDa

NCBI Accession: NP_000283

Pathways: Cellular Glucan Metabolic Process