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PLAGL1 Protein (His tag)

PLAGL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729109
  • Target See all PLAGL1 Proteins
    PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PLAGL1 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PLAGL1 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PLAGL1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
    Alternative Name
    Plagl1 (PLAGL1 Products)
    Synonyms
    PLAGL1 Protein, LOT1 Protein, ZAC Protein, ZAC1 Protein, Lot1 Protein, Zac1 Protein, PLAG1 like zinc finger 1 Protein, uncharacterized LOC100350914 Protein, pleiomorphic adenoma gene-like 1 Protein, PLAGL1 Protein, LOC100350914 Protein, Plagl1 Protein
    Background
    This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.
    Molecular Weight
    44.5 kDa
    NCBI Accession
    NP_002647
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