PPT1 Protein (His tag)

Catalog No. ABIN2729524

Product Details

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PPT1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PPT1 / PPT (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Alternative Name: Ppt1,ppt (PPT1 Products)

Synonyms: CLN1 Protein, INCL Protein, PPT Protein, 9530043G02Rik Protein, AA960502 Protein, C77813 Protein, D4Ertd184e Protein, Ppt Protein, wu:fj17f04 Protein, zgc:63969 Protein, PPT-1 Protein, ppt1 Protein, palmitoyl-protein thioesterase 1 Protein, Palmitoyl-protein thioesterase 1 Protein, palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) Protein, palmitoyl-protein thioesterase 1 L homeolog Protein, PPT1 Protein, MGYG_00692 Protein, Ppt1 Protein, ppt-1 Protein, ppt1 Protein, ppt1.L Protein

Background: The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]

Molecular Weight: 34.2 kDa

NCBI Accession: NP_000301

Pathways: SARS-CoV-2 Protein Interactome