PRDM12 Protein (Myc-DYKDDDDK Tag)
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- Target See all PRDM12 Proteins
- PRDM12 (PR Domain Containing 12 (PRDM12))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRDM12 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PRDM12 / PFM9 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRDM12 Protein
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PR Domain Containing 12 (PRDM12) (AA 2-243) protein (His tag)
PRDM12 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
PR Domain Containing 12 (PRDM12) (AA 1-365) protein (Strep Tag)Crystallography grade PRDM12 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PRDM12 (PR Domain Containing 12 (PRDM12))
- Alternative Name
- Prdm12,pfm9 (PRDM12 Products)
- Synonyms
- PRDM12 Protein, prdm12 Protein, MGC146714 Protein, PFM9 Protein, pfm9 Protein, Gm998 Protein, PR/SET domain 12 Protein, PR domain containing 12 Protein, PR domain containing 12 L homeolog Protein, PR domain containing 12a Protein, PRDM12 Protein, prdm12 Protein, prdm12.L Protein, Prdm12 Protein, prdm12a Protein
- Background
- This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN&aposs) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.
- Molecular Weight
- 40.2 kDa
- NCBI Accession
- NP_067632
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