PTGIS Protein (Myc-DYKDDDDK Tag)
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- Target See all PTGIS Proteins
- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTGIS protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTGIS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTGIS Protein
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Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) (AA 391-500) protein (GST tag)
PTGIS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) (AA 1-500) protein (GST tag)PTGIS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) (AA 1-500) protein (Strep Tag)Crystallography grade PTGIS Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) (AA 1-501) protein (Strep Tag)Crystallography grade PTGIS Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
- Alternative Name
- Ptgis (PTGIS Products)
- Synonyms
- CYP8 Protein, CYP8A1 Protein, PGIS Protein, PTGI Protein, Cyp8 Protein, Cyp8a1 Protein, Pgis Protein, ptgisl Protein, PTGIS Protein, prostaglandin I2 synthase Protein, prostaglandin I2 (prostacyclin) synthase Protein, prostacyclin synthase Protein, PTGIS Protein, Ptgis Protein, ptgis Protein, VDBG_06319 Protein
- Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
- Molecular Weight
- 56.9 kDa
- NCBI Accession
- NP_000952
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