PTPN18 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PTPN18 Proteins
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPN18 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTPN18 / BDP1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPN18 Protein
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Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) (AA 1-351) protein (GST tag)
PTPN18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) (AA 1-460) protein (Strep Tag)Crystallography grade PTPN18 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) (AA 1-453) protein (Strep Tag)Crystallography grade PTPN18 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
- Alternative Name
- Ptpn18,bdp1 (PTPN18 Products)
- Synonyms
- BDP1 Protein, PTP-HSCF Protein, FLP1 Protein, HSCF Protein, PTP-K1 Protein, Ptpk1 Protein, PTP20 Protein, protein tyrosine phosphatase, non-receptor type 18 Protein, PTPN18 Protein, Ptpn18 Protein
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 50.3 kDa
- NCBI Accession
- NP_055184
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