PTPN21 Protein (Myc-DYKDDDDK Tag)
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- Target See all PTPN21 Proteins
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPN21 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTPN21 / PTPD1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPN21 Protein
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Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) (AA 1-1174) protein (Strep Tag)
Crystallography grade PTPN21 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) (AA 1-1176) protein (Strep Tag)Crystallography grade PTPN21 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- Alternative Name
- Ptpn21,ptpd1 (PTPN21 Products)
- Synonyms
- PTPD1 Protein, PTPRL10 Protein, Ptp2E Protein, protein tyrosine phosphatase, non-receptor type 21 Protein, PTPN21 Protein, Ptpn21 Protein
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
- Molecular Weight
- 133.1 kDa
- NCBI Accession
- NP_008970
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