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PTPN7 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

PTPN7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730125
  • Target See all PTPN7 Proteins
    PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 6
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PTPN7 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PTPN7 / HEPTP (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTPN7 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
    Alternative Name
    Ptpn7,heptp (PTPN7 Products)
    Synonyms
    BPTP-4 Protein, HEPTP Protein, LC-PTP Protein, LPTP Protein, PTPNI Protein, C920001D21Rik Protein, Heptp Protein, Lcptp Protein, protein tyrosine phosphatase, non-receptor type 7 Protein, PTPN7 Protein, Ptpn7 Protein
    Background
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    44.8 kDa
    NCBI Accession
    NP_542155
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