PUF60 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730159

Product Details

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PUF60 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PUF60 / SIAHBP1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Alternative Name: Puf60,siahbp1 (PUF60 Products)

Synonyms: FIR Protein, RoBPI Protein, SIAHBP1 Protein, fc21a05 Protein, wu:fc21a05 Protein, wu:fi43a08 Protein, 2410104I19Rik Protein, 2810454F19Rik Protein, Siahbp1 Protein, fe37c05 Protein, repressor Protein, si:ch211-12p8.2 Protein, si:zc12p8.2 Protein, wu:fb33e11 Protein, wu:fe37c05 Protein, zgc:86806 Protein, poly(U) binding splicing factor 60 Protein, poly-U binding splicing factor a Protein, poly-U binding splicing factor 60 Protein, poly-U binding splicing factor b Protein, PUF60 Protein, puf60a Protein, Puf60 Protein, puf60b Protein

Background: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 58 kDa

NCBI Accession: NP_055096