RACGAP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730394

Product Details

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RACGAP1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RACGAP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Alternative Name: Racgap1 (RACGAP1 Products)

Synonyms: CYK4 Protein, HsCYK-4 Protein, ID-GAP Protein, MgcRacGAP Protein, cyk-4 Protein, id-gap Protein, mgcracgap Protein, RACGAP1 Protein, MGC121578 Protein, Gap Protein, RasGAP Protein, Rasa Protein, GAPX Protein, AI227039 Protein, AI327394 Protein, Band25 Protein, GTPase Protein, gtl11 Protein, mKIAA1478 Protein, wu:fb92c08 Protein, zgc:77839 Protein, Rac GTPase activating protein 1 Protein, rac GTPase-activating protein 1 Protein, Rac GTPase activating protein 1 L homeolog Protein, RAS p21 protein activator 1 Protein, Rac GTPase-activating protein 1 Protein, si:ch1073-416j23.1 Protein, RACGAP1 Protein, racgap1 Protein, racgap1.L Protein, racgap1.2.L Protein, racgap1.2 Protein, Rasa1 Protein, Racgap1 Protein, si:ch1073-416j23.1 Protein

Background: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.

Molecular Weight: 70.8 kDa

NCBI Accession: NP_037409

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor