RAE1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730422

Product Details

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RAE1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RAE1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Alternative Name: Rae1 (RAE1 Products)

Synonyms: gle2 Protein, mig14 Protein, mnrp41 Protein, mrnp41 Protein, MRNP41 Protein, zgc:56449 Protein, zgc:77723 Protein, 3230401I12Rik Protein, 41 Protein, D2Ertd342e Protein, MNRP Protein, MNRP41 Protein, MIG14 Protein, Mnrp41 Protein, dJ481F12.3 Protein, dJ800J21.1 Protein, ribonucleic acid export 1 Protein, RAE1 RNA export 1 homolog Protein, ribonucleic acid export 1 L homeolog Protein, rae1 Protein, LOC664096 Protein, RAE1 Protein, rae1.L Protein, Rae1 Protein

Background: Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 40.8 kDa

NCBI Accession: NP_001015885

Pathways: SARS-CoV-2 Protein Interactome