RASA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all RASA1 Proteins
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RASA1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RASA1 / RasGAP (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RASA1 Protein
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RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) protein (GST tag)
RASA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) protein (GST tag)RASA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-1047) protein (Strep Tag)Crystallography grade RASA1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
- Alternative Name
- Rasa1,rasgap (RASA1 Products)
- Synonyms
- CG9209 Protein, D-RasGAP Protein, Dmel\\CG9209 Protein, RAS-GAP Protein, RasGAP Protein, RasGap Protein, rasGap Protein, CM-AVM Protein, CMAVM Protein, GAP Protein, PKWS Protein, RASA Protein, RASGAP Protein, p120GAP Protein, p120RASGAP Protein, GAPX Protein, Rasa Protein, Gap Protein, vacuolar peduncle Protein, RAS p21 protein activator 1 Protein, vap Protein, RASA1 Protein, Rasa1 Protein
- Background
- The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
- Molecular Weight
- 116.2 kDa
- NCBI Accession
- NP_002881
- Pathways
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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