RASD2 Protein (Myc-DYKDDDDK Tag)
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- Target See all RASD2 Proteins
- RASD2 (RASD Family, Member 2 (RASD2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RASD2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RASD2 / TEM2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RASD2 Protein
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RASD Family, Member 2 (RASD2) (AA 1-266) protein (GST tag)
RASD2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
RASD Family, Member 2 (RASD2) (AA 1-263) protein (His tag)Crystallography grade RASD2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
RASD Family, Member 2 (RASD2) (AA 1-263) protein (His tag)Crystallography grade RASD2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RASD2 (RASD Family, Member 2 (RASD2))
- Alternative Name
- Rasd2,tem2 (RASD2 Products)
- Synonyms
- RASD2 Protein, MGC:4834 Protein, Rhes Protein, TEM2 Protein, 4930526B11Rik Protein, AU045414 Protein, TEM-2 Protein, RASD family member 2 Protein, RASD family, member 2 Protein, RASD2 Protein, Rasd2 Protein
- Background
- This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.
- Molecular Weight
- 30.2 kDa
- NCBI Accession
- NP_055125
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