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RASGRP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

RASGRP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730539
  • Target See all RASGRP2 Proteins
    RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 6
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RASGRP2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RASGRP2 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RASGRP2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
    Alternative Name
    Rasgrp2 (RASGRP2 Products)
    Synonyms
    CALDAG-GEFI Protein, CDC25L Protein, xrasgrp2 Protein, RASGRP2 Protein, Caldaggef1 Protein, CalDAG-GEFI Protein, rasgrp2 Protein, RAS guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog Protein, RAS, guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog Protein, RASGRP2 Protein, rasgrp2.S Protein, Rasgrp2 Protein, rasgrp2.L Protein
    Background
    The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
    Molecular Weight
    69.1 kDa
    NCBI Accession
    NP_001092140
    Pathways
    TCR Signaling
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