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RBM8A Protein (Myc-DYKDDDDK Tag)

RBM8A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730625
  • Target See all RBM8A Proteins
    RBM8A (RNA Binding Motif Protein 8A (RBM8A))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RBM8A protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RBM8A / RBM8 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RBM8A Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RBM8A (RNA Binding Motif Protein 8A (RBM8A))
    Alternative Name
    Rbm8a,rbm8 (RBM8A Products)
    Synonyms
    BOV-1A Protein, BOV-1B Protein, BOV-1C Protein, C1DELq21.1 Protein, DEL1q21.1 Protein, MDS014 Protein, RBM8 Protein, RBM8B Protein, TAR Protein, Y14 Protein, ZNRP Protein, ZRNP1 Protein, 2310057C03Rik Protein, AA673428 Protein, Rbm8 Protein, RBM8A Protein, rbm8 Protein, rbm8a Protein, rnp-5 Protein, fb34f03 Protein, wu:fb34f03 Protein, zgc:110525 Protein, rbm8-A Protein, rbm8a-A Protein, rbm8-B Protein, RNA binding motif protein 8A Protein, RNA binding motif protein 8a Protein, RNA binding motif protein 8A S homeolog Protein, RNA binding motif protein 8A L homeolog Protein, RBM8A Protein, Rbm8a Protein, rbm8a Protein, rbm8a.S Protein, rbm8a.L Protein
    Background
    This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.
    Molecular Weight
    19.7 kDa
    NCBI Accession
    NP_005096
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