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ARHGAP8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ARHGAP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730842
  • Target See all ARHGAP8 Proteins
    ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ARHGAP8 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ARHGAP8 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ARHGAP8 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))
    Abstract
    ARHGAP8 Products
    Synonyms
    BPGAP1 Protein, PP610 Protein, 3110043J09Rik Protein, AU043908 Protein, Arhgap8 Protein, C030017C09Rik Protein, C78947 Protein, Protor-1 Protein, Protor1 Protein, Rho GTPase activating protein 8 Protein, proline rich 5 (renal) Protein, proline rich 5 Protein, ARHGAP8 Protein, Arhgap8 Protein, arhgap8 Protein, Prr5 Protein
    Background
    This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
    Molecular Weight
    49.6 kDa
    NCBI Accession
    NP_851852
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