Rhotekin Protein (RTKN) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all Rhotekin (RTKN) Proteins
- Rhotekin (RTKN)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Rhotekin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Rhotekin / RTKN (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RTKN Protein
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Rhotekin (RTKN) (AA 451-549) protein (GST tag)
RTKN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Rhotekin (RTKN) (AA 1-563) protein (Strep Tag)Crystallography grade RTKN Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Rhotekin (RTKN) (AA 1-564) protein (Strep Tag)Crystallography grade RTKN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Rhotekin (RTKN) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RTKN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Rhotekin (RTKN)
- Alternative Name
- Rhotekin,rtkn (RTKN Products)
- Synonyms
- RTKN Protein, rhotekin Protein, RTKN Protein, rtkn Protein, Rtkn Protein
- Background
- This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 61 kDa
- NCBI Accession
- NP_149035
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