RNF2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731042

Product Details

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RNF2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RNF2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Bhatnagar, Gazin, Chamberlain, Ou, Zhu, Tushir, Virbasius, Lin, Zhu, Wajapeyee, Green: "TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein." in: Nature, Vol. 516, Issue 7529, pp. 116-20, (2014) (PubMed).

Target Details

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: Rnf2 (RNF2 Products)

Synonyms: BAP-1 Protein, BAP1 Protein, DING Protein, HIPI3 Protein, RING1B Protein, RING2 Protein, AI326319 Protein, AI450156 Protein, AU019207 Protein, Ring1B Protein, dinG Protein, fa19h05 Protein, ring1b Protein, wu:fa19h05 Protein, wz4556 Protein, bap-1 Protein, bap1 Protein, ding Protein, hipi3 Protein, ring2 Protein, ring finger protein 2 Protein, ring finger protein 2 L homeolog Protein, RNF2 Protein, Rnf2 Protein, rnf2 Protein, rnf2.L Protein

Background: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Molecular Weight: 37.5 kDa

NCBI Accession: NP_009143