RNF213 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731043

Product Details

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RNF213 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RNF213 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Alternative Name: Rnf213 (RNF213 Products)

Synonyms: RNF213 Protein, ALO17 Protein, C17orf27 Protein, KIAA1618 Protein, MYMY2 Protein, MYSTR Protein, NET57 Protein, RGD1308168 Protein, 6030403J01 Protein, D11Ertd759e Protein, mKIAA1554 Protein, E3 ubiquitin-protein ligase RNF213 Protein, ring finger protein 213 Protein, LOC509283 Protein, LOC100626814 Protein, RNF213 Protein, LOC100461067 Protein, Rnf213 Protein

Background: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(217)(p23q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(817)(q24q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants.

Molecular Weight: 118.3 kDa

NCBI Accession: NP_066005