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Septin 5 Protein (SEPT5) (Myc-DYKDDDDK Tag)

SEPT5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731689
  • Target See all Septin 5 (SEPT5) Proteins
    Septin 5 (SEPT5)
    Protein Type
    Recombinant
    Origin
    • 5
    • 2
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Septin 5 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Septin-5 (SEPT5) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SEPT5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Septin 5 (SEPT5)
    Alternative Name
    Septin-5 (Sept5) (SEPT5 Products)
    Synonyms
    sept5 Protein, fj37h04 Protein, zgc:73218 Protein, wu:fj37h04 Protein, SEPT5 Protein, Cdcrel-1 Protein, Cdcrel1 Protein, Pnutl1 Protein, 5-Sep Protein, CDCrel-1A Protein, CDCREL Protein, CDCREL-1 Protein, CDCREL1 Protein, H5 Protein, HCDCREL-1 Protein, PNUTL1 Protein, septin 5a Protein, septin 5 Protein, sept5a Protein, SEPT5 Protein, sept5 Protein, Sept5 Protein
    Background
    This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.
    Molecular Weight
    42.6 kDa
    NCBI Accession
    NP_002679
    Pathways
    Synaptic Vesicle Exocytosis
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