SERPINB6 Protein (His tag)

Catalog No. ABIN2731818

Product Details

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SERPINB6 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SERPINB6 / PI6 protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: < 0.1 EU per μg protein as determined by LAL test

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Alternative Name: Serpinb6,pi6 (SERPINB6 Products)

Synonyms: Serpinb6a Protein, cap Protein, dfnb91 Protein, mstp057 Protein, pi6 Protein, pti Protein, serpinb8 Protein, spi3 Protein, 4930482L21Rik Protein, D330015H01Rik Protein, PI-6 Protein, Serpinb6 Protein, Spi3 Protein, ovalbumin Protein, CAP Protein, DFNB91 Protein, MSTP057 Protein, PI6 Protein, PTI Protein, SPI3 Protein, serpin family B member 6A Protein, serpin family B member 6 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 6a Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 6 Protein, Serpinb6a Protein, serpinb6 Protein, SERPINB6 Protein

Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 60.7 kDa

NCBI Accession: NP_004559