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SETDB1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SETDB1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731883
  • Target See all SETDB1 Proteins
    SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SETDB1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SETDB1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SETDB1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
    Alternative Name
    Setdb1 (SETDB1 Products)
    Synonyms
    ESET Protein, H3-K9-HMTase4 Protein, KG1T Protein, KMT1E Protein, TDRD21 Protein, AU022152 Protein, mKIAA0067 Protein, SETDB1 Protein, NV10069 Protein, fc07d03 Protein, si:ch211-81a5.6 Protein, wu:fc07d03 Protein, im:7143091 Protein, wu:fa04a12 Protein, wu:fj80h02 Protein, zgc:152899 Protein, SET domain bifurcated 1 Protein, SET domain, bifurcated 1 Protein, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 Protein, histone-lysine N-methyltransferase SETDB1 Protein, SET domain, bifurcated 1a Protein, SET domain bifurcated 1 L homeolog Protein, SET domain, bifurcated 1b Protein, SETDB1 Protein, Setdb1 Protein, MLLT11 Protein, LOC100120014 Protein, LOC100461671 Protein, setdb1a Protein, setdb1.L Protein, setdb1b Protein
    Background
    This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].
    Molecular Weight
    143 kDa
    NCBI Accession
    NP_001138887
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