SETMAR Protein (Myc-DYKDDDDK Tag)
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- Target See all SETMAR Proteins
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SETMAR protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SETMAR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SETMAR Protein
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SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-352) protein (GST tag)
SETMAR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-309) protein (Strep Tag)Crystallography grade SETMAR Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-684) protein (Strep Tag)Crystallography grade SETMAR Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SET Domain and Mariner Transposase Fusion Gene (SETMAR) (AA 1-118), (full length) protein (His tag)SETMAR Origin: Human Host: Yeast Recombinant > 90 % SDS
SET Domain and Mariner Transposase Fusion Gene (SETMAR) protein (DYKDDDDK Tag)SETMAR Origin: Human Host: Baculovirus Recombinant EAA, ScA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Alternative Name
- Setmar (SETMAR Products)
- Synonyms
- HsMar1 Protein, METNASE Protein, Mar1 Protein, 5830404F24Rik Protein, Etet2 Protein, SETMAR Protein, zgc:172212 Protein, SET domain and mariner transposase fusion gene Protein, SET domain without mariner transposase fusion Protein, histone-lysine N-methyltransferase SETMAR Protein, SETMAR Protein, Setmar Protein, LOC470738 Protein, setmar Protein, LOC703880 Protein, LOC100447656 Protein, LOC100586616 Protein
- Background
- This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
- Molecular Weight
- 77.9 kDa
- NCBI Accession
- NP_006506
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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