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SH3BP1 Protein (Myc-DYKDDDDK Tag)

SH3BP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731971
  • Target See all SH3BP1 Proteins
    SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SH3BP1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SH3BP1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SH3BP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
    Alternative Name
    Sh3bp1 (SH3BP1 Products)
    Synonyms
    ARHGAP43 Protein, 3BP-1 Protein, SH3BP1 Protein, SH3 domain binding protein 1 Protein, SH3-domain binding protein 1 Protein, SH3 domain-binding protein 1 Protein, SH3BP1 Protein, Sh3bp1 Protein, LOC100398528 Protein
    Background
    This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein&aposs association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.
    Molecular Weight
    75.5 kDa
    NCBI Accession
    NP_061830
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