SLC12A3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all SLC12A3 Proteins
- SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SLC12A3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SLC12A3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SLC12A3 Protein
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Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 832-1002) protein (His tag)
Crystallography grade SLC12A3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 1-135) protein (His tag)Crystallography grade SLC12A3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 682-1021) protein (His tag)Crystallography grade SLC12A3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 1-133) protein (His tag)Crystallography grade SLC12A3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 1-1021) protein (Strep Tag)Crystallography grade SLC12A3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3) (AA 1-1002) protein (Strep Tag)Crystallography grade SLC12A3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))
- Alternative Name
- Slc12a3 (SLC12A3 Products)
- Synonyms
- SLC12A3 Protein, slc12a3 Protein, DKFZp469N2315 Protein, NCC Protein, NCCT Protein, TSC Protein, AI035291 Protein, solute carrier family 12 member 3 Protein, solute carrier family 12 (sodium/chloride transporter), member 3 Protein, solute carrier family 12, member 3 Protein, SLC12A3 Protein, slc12a3.2 Protein, Slc12a3 Protein
- Background
- This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 113.7 kDa
- NCBI Accession
- NP_000330
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