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SMOX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

SMOX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732257
  • Target See all SMOX Proteins
    SMOX (Spermine Oxidase (SMOX))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 2
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SMOX protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SMOX (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SMOX Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SMOX (Spermine Oxidase (SMOX))
    Alternative Name
    Smox (SMOX Products)
    Synonyms
    cb1027 Protein, wu:fq32f10 Protein, zgc:77167 Protein, MGC81392 Protein, APAO Protein, ATPAO1 Protein, MSH12.17 Protein, MSH12_17 Protein, polyamine oxidase 1 Protein, C20orf16 Protein, PAO Protein, PAO-1 Protein, PAOH1 Protein, SMO Protein, B130066H01Rik Protein, PAOh1 Protein, spermine oxidase Protein, spermine oxidase S homeolog Protein, polyamine oxidase 1 Protein, smox Protein, SMOX Protein, smox.S Protein, PAO1 Protein, Smox Protein
    Background
    Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.
    Molecular Weight
    55.9 kDa
    NCBI Accession
    NP_787034
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