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SMPD1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SMPD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732260
  • Target See all SMPD1 Proteins
    SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SMPD1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SMPD1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SMPD1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
    Alternative Name
    Smpd1 (SMPD1 Products)
    Synonyms
    ASM Protein, ASMASE Protein, NPD Protein, A-SMase Protein, Zn-SMase Protein, aSMase Protein, SMPD1 Protein, sphingomyelin phosphodiesterase 1 Protein, sphingomyelin phosphodiesterase 1, acid lysosomal Protein, sphingomyelin phosphodiesterase Protein, SMPD1 Protein, Smpd1 Protein, LOC5578088 Protein
    Background
    The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
    Molecular Weight
    65 kDa
    NCBI Accession
    NP_000534
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