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SF3B2 Protein (Myc-DYKDDDDK Tag)

SF3B2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732607
  • Target See all SF3B2 Proteins
    SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SF3B2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Splicing factor 3b, subunit 2, 145 kDa (SF3B2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SF3B2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))
    Abstract
    SF3B2 Products
    Synonyms
    145kDa Protein, 2610311M13Rik Protein, 2810441F20Rik Protein, B230398H18Rik Protein, SAP145 Protein, SF3b1 Protein, SF3b145 Protein, SF3b150 Protein, SF3B2 Protein, cus1 Protein, sap145 Protein, sf3b145 Protein, sf3b150 Protein, Cus1 Protein, SF3B145 Protein, splicing factor 3b, subunit 2 Protein, splicing factor 3b subunit 2 Protein, splicing factor 3B subunit 2 Protein, splicing factor 3b subunit 2 L homeolog Protein, Sf3b2 Protein, SF3B2 Protein, LOC714747 Protein, sf3b2.L Protein, sf3b2 Protein
    Background
    This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
    Molecular Weight
    100 kDa
    NCBI Accession
    NP_006833
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