TBXAS1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733330

Product Details

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TBXAS1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TBXAS1 (transcript variant TXS-I) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: Tbxas1 (TBXAS1 Products)

Synonyms: thas Protein, TBXAS1 Protein, wu:fk19d08 Protein, zgc:136708 Protein, BDPLT14 Protein, CYP5 Protein, CYP5A1 Protein, GHOSAL Protein, THAS Protein, TS Protein, TXAS Protein, TXS Protein, thromboxane-A synthase Protein, Thromboxane-A synthase Protein, thromboxane A synthase 1 Protein, thromboxane A synthase 1 (platelet) Protein, thromboxane A synthase 1, platelet Protein, PTRG_00454 Protein, PTRG_06796 Protein, thas Protein, TBXAS1 Protein, tbxas1 Protein, Tbxas1 Protein

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 60.5 kDa

NCBI Accession: NP_001052