TDP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all TDP1 Proteins
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TDP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TDP1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TDP1 Protein
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Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (GST tag)
TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 121-218) protein (GST tag)TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (Strep Tag)Crystallography grade TDP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-609) protein (Strep Tag)Crystallography grade TDP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) proteinTDP1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA, IP
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TDP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Alternative Name
- Tdp1 (TDP1 Products)
- Synonyms
- 2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
- Background
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).
- Molecular Weight
- 68.2 kDa
- NCBI Accession
- NP_001008744
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