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TFE3 Protein (Myc-DYKDDDDK Tag)

TFE3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733465
  • Target See all TFE3 Proteins
    TFE3 (Transcription Factor E3 (TFE3))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This TFE3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TFE3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TFE3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TFE3 (Transcription Factor E3 (TFE3))
    Alternative Name
    Tfe3 (TFE3 Products)
    Synonyms
    RCCP2 Protein, RCCX1 Protein, TFEA Protein, bHLHe33 Protein, F830016E06Rik Protein, Tcfe3 Protein, Tfe-3 Protein, RGD1559642 Protein, cb873 Protein, zgc:109815 Protein, transcription factor binding to IGHM enhancer 3 Protein, transcription factor E3 Protein, transcription factor binding to IGHM enhancer 3 S homeolog Protein, transcription factor binding to IGHM enhancer 3a Protein, TFE3 Protein, Tfe3 Protein, tfe3.S Protein, tfe3a Protein
    Background
    Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    61.3 kDa
    NCBI Accession
    NP_006512
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