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THG1L Protein (Myc-DYKDDDDK Tag)

THG1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733557
  • Target See all THG1L Proteins
    THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This THG1L protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human THG1L / ICF45 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product THG1L Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
    Alternative Name
    Thg1l,icf45 (THG1L Products)
    Synonyms
    ICF45 Protein, IHG-1 Protein, 1700121M19Rik Protein, 5730409G07Rik Protein, AA387658 Protein, tRNA-histidine guanylyltransferase 1 like Protein, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Protein, tRNA-histidine guanylyltransferase 1-like Protein, THG1L Protein, Thg1l Protein
    Background
    The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    34.7 kDa
    NCBI Accession
    NP_060342
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