TPK1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all TPK1 Proteins
- TPK1 (Thiamin Pyrophosphokinase 1 (TPK1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TPK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Thiamine pyrophosphokinase 1 (TPK1) (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TPK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 10, pp. 1656-62, (2014) (PubMed).
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The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 10, pp. 1656-62, (2014) (PubMed).
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- Target
- TPK1 (Thiamin Pyrophosphokinase 1 (TPK1))
- Alternative Name
- Thiamine Pyrophosphokinase 1 (Tpk1) (TPK1 Products)
- Synonyms
- zgc:101685 Protein, TPK1 Protein, tpk1 Protein, HTPK1 Protein, PP20 Protein, THMD5 Protein, thiamin pyrophosphokinase 1 Protein, Thiamin pyrophosphokinase 1 Protein, thiamine pyrophosphokinase Protein, TPK1 Protein, tpk1 Protein, PVX_099630 Protein, CpipJ_CPIJ015475 Protein, MCYG_04241 Protein, LOC100285737 Protein, tpk-1 Protein, Tpk1 Protein
- Background
- This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 27.1 kDa
- NCBI Accession
- NP_071890
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