TIA1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733699

Product Details

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TIA1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TIA1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Alternative Name: Tia1 (TIA1 Products)

Synonyms: tia1 Protein, 2310050N03Rik Protein, AI256674 Protein, TIA-1 Protein, mTIA-1 Protein, WDM Protein, TIAL1 Protein, TIAR Protein, tia-1 Protein, nucleolysin TIA-1 isoform p40 Protein, hypothetical protein Protein, nucleolysin TIAR Protein, nucleolysin tia-1 Protein, nucleolysin TIA-1 Protein, cytotoxic granule-associated RNA binding protein 1 Protein, TIA1 cytotoxic granule associated RNA binding protein Protein, TIA1 cytotoxic granule-associated RNA binding protein Protein, TIA1 cytotoxic granule-associated RNA binding protein L homeolog Protein, PTRG_10065 Protein, PGTG_08590 Protein, LOC5568274 Protein, CpipJ_CPIJ013665 Protein, VDBG_07004 Protein, MGYG_03339 Protein, Tsp_15456 Protein, tia1 Protein, Tia1 Protein, TIA1 Protein, tia1.L Protein

Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Molecular Weight: 42.8 kDa

NCBI Accession: NP_071505