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TCOF1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

TCOF1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734193
  • Target See all TCOF1 Proteins
    TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 2
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TCOF1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Treacle protein / TCOF1 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TCOF1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
    Alternative Name
    Treacle Protein,tcof1 (TCOF1 Products)
    Synonyms
    TCOF1 Protein, AA408847 Protein, AW209012 Protein, treacle Protein, MFD1 Protein, TCS1 Protein, treacle ribosome biogenesis factor 1 Protein, Tcof1 Protein, TCOF1 Protein
    Background
    This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    96.6 kDa
    NCBI Accession
    NP_001008657
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