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TPSG1 Protein (Myc-DYKDDDDK Tag)

TPSG1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734413
  • Target See all TPSG1 Proteins
    TPSG1 (Tryptase gamma 1 (TPSG1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 4
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TPSG1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Tryptase gamma (TPSG1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TPSG1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TPSG1 (Tryptase gamma 1 (TPSG1))
    Alternative Name
    Tryptase gamma (Tpsg1) (TPSG1 Products)
    Synonyms
    mpn Protein, PRSS31 Protein, TMT Protein, trpA Protein, Prss31 Protein, Tmt Protein, tryptase gamma 1 S homeolog Protein, tryptase gamma 1 Protein, tpsg1.S Protein, tpsg1 Protein, TPSG1 Protein, Tpsg1 Protein
    Background
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
    Molecular Weight
    32 kDa
    NCBI Accession
    NP_036599
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