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Tumor Protein p73 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

TP73 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734636
  • Target See all Tumor Protein p73 (TP73) Proteins
    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Tumor Protein p73 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Tumor protein p73 (TP73) (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TP73 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
    Abstract
    TP73 Products
    Synonyms
    P73 Protein, Trp73 Protein, TP73 Protein, tp73 Protein, Tp73 Protein, p73 Protein, TAp73 Protein, zp73theta Protein, tumor protein p73 Protein, transformation related protein 73 Protein, TP73 Protein, Tp73 Protein, tp73 Protein, Trp73 Protein
    Background
    This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
    Molecular Weight
    69.4 kDa
    NCBI Accession
    NP_005418
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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