TXNIP Protein (Myc-DYKDDDDK Tag)
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- Target See all TXNIP Proteins
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TXNIP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TXNIP / VDUP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TXNIP Protein
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Thioredoxin Interacting Protein (TXNIP) (AA 22-382) protein (His-IF2DI Tag)
TXNIP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Thioredoxin Interacting Protein (TXNIP) (AA 1-391) protein (GST tag)TXNIP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thioredoxin Interacting Protein (TXNIP) (AA 1-391) protein (His tag)Crystallography grade TXNIP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Thioredoxin Interacting Protein (TXNIP) (AA 1-397) protein (His tag)Crystallography grade TXNIP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- Alternative Name
- Txnip,vdup1 (TXNIP Products)
- Synonyms
- EST01027 Protein, HHCPA78 Protein, THIF Protein, VDUP1 Protein, Gm348 Protein, Trf3 Protein, TBP2 Protein, TRF3 Protein, 1200008J08Rik Protein, AA682105 Protein, Hyplip1 Protein, Tbp-2 Protein, Vdup1 Protein, sb:cb368 Protein, txnip Protein, thioredoxin interacting protein Protein, TATA box binding protein like 2 Protein, TATA-box binding protein like 2 Protein, thioredoxin interacting protein L homeolog Protein, thioredoxin interacting protein a Protein, TXNIP Protein, Tbpl2 Protein, TBPL2 Protein, Txnip Protein, txnip.L Protein, txnip Protein, txnipa Protein
- Background
- This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
- Molecular Weight
- 43.5 kDa
- NCBI Accession
- NP_006463
- Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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