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USP8 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

USP8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2734893
  • Target See all USP8 Proteins
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This USP8 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Ubiquitin specific peptidase 8 (USP8), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product USP8 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Abstract
    USP8 Products
    Synonyms
    HumORF8 Protein, UBPY Protein, AI574262 Protein, AW557536 Protein, Ubpy Protein, mKIAA0055 Protein, ubiquitin carboxyl-terminal hydrolase 8 Protein, ubiquitin specific peptidase 8 Protein, LOC9310109 Protein, MGYG_00369 Protein, USP8 Protein, Usp8 Protein
    Background
    This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
    Molecular Weight
    127.3 kDa
    NCBI Accession
    NP_001122083
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