UBXN1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734926

Product Details

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UBXN1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UBXN1 / SAKS1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Alternative Name: Ubxn1,saks1 (UBXN1 Products)

Synonyms: 2B28 Protein, SAKS1 Protein, UBXD10 Protein, 4930455J02Rik Protein, D19Ertd721e Protein, T25529 Protein, RGD1309471 Protein, fb49a05 Protein, wu:fb49a05 Protein, zgc:77531 Protein, UBX domain protein 1 Protein, UBXN1 Protein, Ubxn1 Protein, ubxn1 Protein

Background: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 34.9 kDa

NCBI Accession: NP_056937