UGT1A6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734968

Product Details

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UGT1A6 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UDP glucuronosyltransferase 1 family, polypeptide A6 (UGT1A6), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Abstract: UGT1A6 Products

Synonyms: GNT1 Protein, HLUGP Protein, HLUGP1 Protein, UDPGT Protein, UDPGT 1-6 Protein, UGT1 Protein, UGT1A6S Protein, UGT1F Protein, UGT1A10 Protein, UGT1A6 Protein, UGT1A7 Protein, UGT1A8 Protein, UGT1A9 Protein, DKFZP469F071 Protein, UGT1A5 Protein, UGT Protein, Udpgt Protein, Ugt1 Protein, Ugt1a7 Protein, UGT1-06 Protein, UGT1.6 Protein, Ugt1a6b Protein, Ugt1a6 Protein, UDP glucuronosyltransferase family 1 member A6 Protein, UDP glucuronosyltransferase family 1 member A1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A6 Protein, UDP-glucuronosyltransferase 1-1 Protein, UDP glucuronosyltransferase 1 family, polypeptide A6 S homeolog Protein, UDP-glucuronosyltransferase 1-6 Protein, UGT1A6 Protein, UGT1A1 Protein, LOC739942 Protein, ugt1a6.S Protein, ugt1a6 Protein, LOC100481084 Protein, Ugt1a6 Protein, UGT1-6 Protein, LOC100731122 Protein

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Molecular Weight: 29.5 kDa

NCBI Accession: NP_995584

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha