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UHRF2 Protein (Myc-DYKDDDDK Tag)

UHRF2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735002
  • Target See all UHRF2 Proteins
    UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This UHRF2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human UHRF2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product UHRF2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
    Alternative Name
    Uhrf2 (UHRF2 Products)
    Synonyms
    NIRF Protein, RNF107 Protein, URF2 Protein, 2310065A22Rik Protein, AI426270 Protein, AW214556 Protein, D130071B19Rik Protein, Nirf Protein, ubiquitin like with PHD and ring finger domains 2 Protein, ubiquitin-like, containing PHD and RING finger domains 2 Protein, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog Protein, UHRF2 Protein, Uhrf2 Protein, uhrf2.L Protein
    Background
    This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
    Molecular Weight
    89.8 kDa
    NCBI Accession
    NP_690856
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